Researchers say these effects occur in patients who overdose on paracetamol.
Paracetamol is one of the trusted pain relief and pain relief medications. Proven for decades, these pills work fast and hassle-free. But experts have issued a shocking health warning to people who regularly take paracetamol.The new research was conducted by a team University of Edinburgh, observed the effects of taking the drug on mice and concluded that it caused damage in vivo. The team said the findings could inform research into therapies to counteract the harm caused by the drug.
Researchers warn that these effects can occur in patients who take an overdose. Four grams of paracetamol per day is a normal dose for people with chronic pain.
The study said: “Scientists at the University of Edinburgh studied the effects of paracetamol on liver cells in human and mouse tissue. Tests showed that in some cases paracetamol can damage the liver by damaging important structural connections between neighboring cells in the organ. .”
“When these cell wall connections, called tight junctions, are disrupted, liver tissue structure is damaged and cells cannot function properly and may even die,” it adds.
This is the first study to link paracetamol toxicity to liver damage, which is similar to conditions such as hepatitis, cirrhosis and cancer.
The study, involving researchers from the Universities of Edinburgh, Oslo and Scotland’s National Blood Transfusion Service, was published in the journal Scientific Reports.
