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A new Hampshire Man who lived with gene-edited pig kidney for record 271 days is resuming dialysis, doctors Said on Monday.
Tim Andrews, 67, had his organ removed on Oct. 23 due to declining organ function, according to Mass General Brigham.
Andrews’ transplant team called him “a selfless medical pioneer and an inspiration.” patients With kidney failure. his experience is coming in handy researcher In his pursuit of animal-to-human transplantation.
Andrews’ experience reflects the lessons researchers have learned with each Use In which is called xenotransplantation. The first attempts to make pig organs more humane by gene-editing them – two hearts and two kidneys – were short-lived.
Then researchers began to consider patients who were not as ill as prior recipients of these experiments—and a Alabama The woman’s pig kidney survived for 130 days before being removed last spring, breaking Andrews’ record.
More than 100,000 people are most in need of a kidney. We Transplant lists, and thousands die waiting.
Andrews, of harmonyNew Hampshire, knew it was especially difficult to match her blood type and looked for an option to qualify for Mass General’s xenotransplant pilot study. His doctors said he remains on the transplant list.
In June, the Mass General team transplanted a pig kidney into another New Hampshire man, who remains in good condition. The pilot study is scheduled to conclude with a third pig kidney transplant later this year.
Two companies, Eugenesis and United Therapeutics, are preparing to begin more rigorous clinical trials of pig kidney transplants.
surgeons In China Also working in this new area is a pig kidney transplant reported last spring and a separately transplanted pig liver that had to be removed after 38 days.