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Saquon Barkley scored two touchdowns philadelphia eagles defeated divisional rivals New York Giants 38-20.
However, the game was eclipsed by a serious ankle injury to Giants rookie Cam Skattebo.
The running back scored a touchdown in the first quarter but was taken out in the second with some running issues.
Barkley rushed for 150 yards and a score against his former team, added 24 yards and another touchdown through the air, before his own injury allowed back-up Tank Bigsby to also top 100 yards receiving.
Jalen Hurts threw two touchdowns to tight end Dallas Goedert and one to Jahan Dotson.
Derrick Henry scored two rushing touchdowns as the Baltimore Ravens broke the form book with a 30–16 victory against the Chicago Bears.
The Ravens were on a four-game losing streak, while the Bears, in contrast, had won their last four games.
James Cook Capped 216-yard running display with two touchdowns buffalo bill Defeated the Carolina Panthers 40–9. quarterback josh allen Also ran in two scores and threw the second to Khalil Shakir.
The New York Jets won their first game of the season when Breece Hall made a tough tackle to Mason Taylor in the end zone, securing a 39–38 victory over the Cincinnati Bengals.
This occurred on the same day that the death of former Jets center Nick Mangold was announced, aged just 41, due to complications from kidney disease.
A tearful former Jets coach Rex Ryan said on ESPN’s pre-game show: “It’s so cruel. Such a great young man. He was amazing, and so young. I feel so bad for his wife and family.”
The Indianapolis Colts improved to 7–1 with a 38–14 win over fellow AFC South team the Tennessee Titans. Jonathan Taylor ran for 153 yards and two touchdowns on just 12 carries and also caught one of Daniel Jones’ three touchdown passes.
Rookie running back RJ Harvey scored three touchdowns as the Denver Broncos defeated the injury-plagued Dallas Cowboys 44–24. Bo Nix threw four touchdown passes, two of which were to Harvey and receiver Troy Franklin.
With quarterback C.J. Stroud rushing for 318 yards and two touchdowns, the Houston Texans surprised the in-form San Francisco 49ers by defeating them 26–15.
The Miami Dolphins ended a three-game losing streak with a dominant 34–10 win over the Atlanta Falcons.
The star of the show was Tua Tagovailoa with four touchdown passes, as the Falcons have now lost back-to-back games.
The New England Patriots made it five straight wins after an easy 32-13 victory over the Cleveland Browns and the Tampa Bay Buccaneers beat NFC South rivals New Orleans Saints 23-3.