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coffee Alcohol drinkers may live five years longer than those who abstain hot drinksA study has shown.
drink a maximum of four cups coffee biological may slow down one day Ageing By lengthening telomeres – structures that protect the ends of chromosomes. Short telomere length in these cells is associated with higher risk of certain age-related diseases and is considered a marker of cellular senescence. Ageing,
but beyond this quota four cups a day – equivalent to 400 mg/day caffeine which one is that maximum recommended By NHS – No benefit found.
Researchers suggest powerful antioxidant and anti-inflammatory compounds in it coffee May be responsible for biological aging and lengthening of telomeres.
The study, published in the journal BMJ Mental Health, looked specifically at the effect of coffee on the aging of people with severe mental illness by looking at their telomere length.
“In moderation, coffee consumption may have a positive effect, but in larger amounts it has the opposite effect. Coffee consumption up to the recommended cup per day limit was associated with a five-year shorter lifespan compared to non-coffee drinkers,” the study authors said.
Telomeres sit at the ends of chromosomes to prevent them from fraying or fraying – like the plastic tip at the end of a shoelace.
Telomeres shorten as we age, but this process accelerates in people with major mental disorders such as psychosis, schizophrenia and bipolar disorder, researchers say.
These structures are sensitive to diet and possibly to coffee, which, if consumed in moderation, is associated with various health benefits.
Data from 436 adult participants from the Norwegian Thematically Organized Psychosis (TOP) study were included. Of the participants, 259 had schizophrenia; The remainder (177) had affective disorders, including bipolar disorder and major depressive disorder with psychosis.
Participants were asked how much coffee they drank a day and were divided into four groups: zero, one to two cups, three to four cups, and five or more cups.
Using blood samples the researchers measured telomere length in white blood cells and, after adjusting for age, gender, ethnicity, tobacco use, type of mental poor health and drug treatment, found that those who drank four cups a day had telomere length equivalent to five years younger biological age than non-coffee drinkers.
People who drank more than five cups of coffee a day had more cellular damage.
Researchers suggest that the anti-aging benefits of coffee are due to its antioxidant properties.
“Telomeres are highly sensitive to both oxidative stress and inflammation, highlighting how coffee consumption may help preserve cellular aging in populations whose pathophysiology may predispose them to accelerated rates of aging,” the researchers report.
But Dr Elizabeth Akam, Senior Teaching Fellow in Biosciences at Loughborough University, who was not involved in the study, suggested that researchers should have looked at compounds in coffee, such as caffeineIn the blood.
“A notable limitation of this study is that it treats ‘coffee’ as if it were a single substance. However, coffee contains many different compounds, and we do not know which of these, in what doses, were given, or how much actually ended up in the bloodstream,” she said.