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Study finds link between male infertility and cancer risk in families

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Study finds link between male infertility and cancer risk in families

Families of men diagnosed with infertility may be at higher risk of certain cancers (Representative)

New Delhi:

Families of men diagnosed with infertility may be at higher risk for certain cancers, including colon and testicular cancer, a new study suggests.

While it’s known that men with infertility tend to have more health problems, including cancer, heart disease and related conditions, and autoimmune diseases, the researchers said they wanted to examine whether their families were at greater risk for these conditions. high risk.

The team says the results generated by the algorithm could help develop a more personalized approach to assessing cancer risk, helping to prevent cancer more effectively.

The findings may also prompt further conversations among families of infertile men and their doctors, they said.

Studies have found that families with infertile men are most likely to develop cancers such as bone and joint cancer, soft tissue cancer, colon cancer and testicular cancer.

For the study, researchers used a Utah population database that contains genetic and public health information. The database, hosted by the Huntsman Cancer Institute at the University of Utah, contains a large collection of Utah family histories in which family members are associated with demographic and medical information.

The research team studied parents, siblings, children, as well as aunts, uncles and cousins ​​of men diagnosed with infertility.

Joemy Ramsay, a researcher at the institute and lead researcher on the study published in the journal Human Reproduction, explains that because family members share the same genetics, environment and lifestyle, it’s easier to identify effects Factors that contribute to their cancer risk.

Once general risks are assessed, she said, the causes can be more accurately assessed to understand their role in cancer diagnosis.

The researchers looked at several types of cancer and developed an algorithm that could group similar cancers by identifying about 13 characteristic patterns. They said the patterns were identified by looking at similar risks for multiple cancers in families rather than looking at one cancer type.

“Cancer and subfertility are complex diseases and processes,” Ramsey said. “This approach helps create similar groups of families, making it easier to discover why one family is more susceptible to certain diseases than others.” She added that while the link between male infertility and cancer risk is not complete, Be clear, but it’s important to have these conversations with your family and express concerns to your doctor.

Ramsey said further research is needed to establish this link, as understanding its causes could eventually lead to more personalized treatments, screening and prevention courses.

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

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