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MPox symptoms explained: from fever to painful skin rashes and blisters

KANIKA SINGH RATHORE, 08/12/202508/12/2025

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The UK Health Protection Agency (UKHSA) says A new strain of mpox has been found In England.

Experts say the infection found in a person who recently returned from Asia is the latest evidence of how the virus is spreading and evolving globally.

So what mpoxAnd should we be worried about it?

What is MPOX?

“Mpox, formerly known as monkeypox, is a rare infection most commonly found in parts of central and eastern Africa,” says Dr Michael Brady, national adviser for LGBT health at NHS England and consultant in sexual health and HIV at King’s College Hospital, London.

“Mpox can spread from one person to another through any close physical contact with blisters or scabs.

“Once infected with mpox, it usually takes five to 21 days for the first symptoms to appear.”

The virus is 'zoonotic'

The virus is ‘zoonotic’ ,AP/R,

Dr. John Roberts, Professor of Health Security University of the West of Englandstated that Mpox “was first observed in laboratory monkeys in the late 1950s, with a human case noted in the 1970s”.

“The virus is ‘zoonotic’ – meaning it can affect a variety of animals, including humans, although cases in humans are rare.”

what are the symptoms?

“The first symptoms of mpox include high temperature, headache, muscle and back pain, swollen glands, shivering, tiredness, and joint pain,” says Brady.

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“A rash usually appears one to five days after the first symptoms and can occur on any part of the body.”

The rash then changes from flat sores to raised bumps, then fluid-filled blisters, often confused with chicken pox, and finally, scabs that eventually fall off.

MPox can develop into more serious conditions, especially in some immunocompromised individuals, as they are more likely to experience severe symptoms and complications.

Rash and blisters on hands due to mpox infection

Rash and blisters on hands due to mpox infection ,AP/R,

“Although most cases of mpox are mild, individuals with weakened immune systems, people who are pregnant or those with underlying health conditions are at higher risk of serious complications,” says Dr Bruno Sylvester Lopes, lecturer in microbiology at Teesside University and researcher in pathogen transmission and molecular epidemiology.

“Potential complications include secondary infections, where scratching or improper care can lead to bacterial infection in wounds or blisters.

“And, in rare cases, infection can lead to systemic complications such as sepsis.”

Who is most at risk?

Dr Katherine Basford at ASDA Online Doctor said those most at risk are “those in close contact with someone with MPOX, including household members, sexual partners, as well as health care workers, men who have sex with men, people with weakened immune systems and individuals in areas where MPOX is spreading.”

“People who have recently traveled to, or who have been in close contact with someone who has recently traveled to, areas of the Middle East or Africa “Where there is an outbreak of mpox, the risk of contracting mpox is higher.”

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How can the symptoms be treated?

“Use over-the-counter pain relievers, such as acetaminophen or ibuprofen, to reduce fever and ease body aches,” advises Lopes. “Keep the rash clean and covered to prevent infection and avoid scratching to reduce the risk of scarring and further infection.”

It is also important to stay hydrated and see your doctor if symptoms worsen.

“Drink plenty of fluids to stay hydrated, especially if a fever or rash is affecting eating or drinking,” advises Lopes. “Consult your GP to get medical advice for specific treatment options and to discuss the possible use of antiviral medications if symptoms are severe.

“And, most importantly, follow isolation guidelines to prevent spreading the virus to others unless you are no longer infectious.”

What are the chances of me catching it in the UK?

“The risk to members of the public in the UK is low,” Roberts explains.

“Travelers returning from countries experiencing cases should be cautious and report symptoms to a health care professional, especially if they have been in direct contact with a known or suspected case.”

Should I be worried about mpox while traveling?

“It is important to follow general advice on safe travel when traveling to the country,” says Roberts. “If traveling to an affected country, specific precautions are advised and can be found on the NaTHNac website.

“Anyone traveling to work in healthcare in an affected country should register with the UKHSA Returning Workers Scheme.”

Uk blistersexplainedfevermpoxpainfulrashesskinsymptoms

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