According to a new study, air pollution is associated with increasing risk of development of dementia.
Fine particles in the air Research can contribute to the disastrous forms of the disease, showing that by promoting toxic groups of protein in the brain.
Exposure for air particles This makes more and more likely to be wrong in the clump, which can then destroy nerve cells in the brain. This is a common cause of levy body dementia, which Researchers describe In the form of a “destructive and rapidly prevalent neurodynative disorder”.
This is the second most common form of the disease after Alzheimer’s.
In light of conclusions, Scientist Call for a concrete effort for improvement Air By cutting emissions, improving wildlife management, and reducing wood burns in homes.
Neurologist at the University of Johns Hopkins and the head investigator of the study, Dr. Xiaobo Mao said: “Unlike age or genetics, this is something we can change.”
“The most direct implication is that there are clean air policies Brain Health policies, “that told Mentor,
To attract their findings, researchers first analyzed the hospital records of 56.5 million American Medicare PatientsLooking at those who were admitted with protein damage between 2000 and 2014. By cross-reversing symptoms with patients’ zip code, they were able to estimate their long-term risk to PM2.5 pollution – Airborne particles smaller than 2.5 thousandth of one millimeter.
They eliminated prolonged risk for particles, which could be breathed in the lungs, increased the risk of levy body dementia.
Levy bodies refer to unusual clumps that carry DiseaseWhich are made of a protein called alpha-consucelein. While protein is necessary to regulate the function of the brain, this may be wrong, which means that it assumes the wrong structure and is harmful.
They can kill nerve cells and cause diseases by spreading through the brain.
To confirm their findings, the researchers tested their theory on mice by exposing PM2.5 pollution every other day for ten months. There were some normal mice, while others were genetically modified to prevent them from the production of alpha-consuce.
The experiment noticed that nerve cells die in normal mice, causing brain shrinkage and cognitive decline. Meanwhile, genetically modified mice showed very little changes.
Further research on mice has shown that PM2.5 pollution was running the formation of toxic groups of alpha-musiclin which were bored with the similarity of levy bodies in humans. These findings are considered a hypnotic evidence despite being confirmed in mice.
“Our findings have a deep implication for prevention because they recognize Air pollution As a convertible risk factor for levy body dementia, ”said Dr. Mao.
“By reducing our collective risk to air pollution, we can potentially reduce the risk of developing these destructive neurodizing conditions on population-wide scale.”