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Inflammation is at the root of Covid and arthritis symptoms
Inflammation is the body’s protective response to injury or infection, but sometimes it gets out of control, causing problems in diseases like COVID-19, rheumatoid arthritis (RA), and osteoarthritis (OA). Scientists have discovered that these three diseases cause similar patterns inside the body, causing inflammation, pain, and tissue damage.
Given the effectiveness of ivermectin against COVID-19, it should not be surprising that ivermectin is showing remarkably promising results in the treatment of arthritis.
covid and arthritis
When someone has COVID-19, RA, or OA, their immune system releases chemicals called cytokines. Cytokines are signaling proteins that the body uses to summon immune cells to fight infection or heal injury. In these conditions, cytokines become overactive and too many immune cells accumulate, leading to inflammation that can cause injury instead of healing.
What causes inflammation: Inflammatory cytokine triad: TNF-AIL-6, and IL-1b
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Tumor necrosis factor-alpha (TNF-)A,A powerful chemical messenger that signals inflammation. When released in large amounts, it can cause redness, swelling, and pain.
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Interleukin-6 (IL-6):Directs many immune responses, including fever and production of protective proteins. Excess IL-6 often results in more inflammation and chronic disease.
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Interleukin-1 beta (1b,Like TNF-α and IL-6, IL-1β increases inflammation and contributes to tissue damage. High levels are common in chronic diseases.
This tridosha appears to be elevated in COVID-19 (as part of the “cytokine storm”), RA (causing inflammation and damage to the joints), and OA (resulting in chronic joint pain and wear and tear).
Arthritis and COVID: Common Signaling Pathways
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NF-OfB (nuclear factor kappa-light-chain-enhancer of activated B cells):Acts as a master switch inside the cells. Hyperactivity leads to continued inflammation and tissue damage.
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MAPK (Mitogen-Activated Protein Kinase):A chain-reaction system that spreads inflammatory signals throughout the cell. Branches such as p38, ERK1/2, and JNK enhance cytokine production.
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Jake/State Route:Proteins that send messages from cytokines, such as IL-6, to the cell nucleus, causing more inflammation. JAK inhibitors may block this step to control inflammation in COVID-19 and RA.
Anti-inflammatory effects of ivermectin
Initially developed to kill parasites, studies show that ivermectin also helps control inflammation. How does this happen you may ask:
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NF-OfB Pathway Barrier:Blocks the master switch, reducing inflammation and tissue damage.
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Direct Cytokine Suppression:Reduces levels of TNF-α, IL-6 and IL-1β, limiting harmful inflammation.
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MAPK Pathway Modulation:Stops the inflammatory chain reaction within cells.
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HOW/STATE PATHWAY INTERFERENCE:Slows down the JAK/STAT protein, which puts the brakes on chronic inflammation. Beneficial in COVID-19 and RA.
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Novel integrin-based mechanisms:Another may block the “gate” that inflammatory messengers use to increase tissue damage.
Because COVID-19, RA, and OA share similar intrinsic signaling pathways that increase inflammation, drugs like ivermectin that block these steps could potentially help treat all three.
Where to get American made ivermectin
For over 30 years, Ivermectin has been trusted worldwide – Nobel Prize-winning, FDA-approved, and proven safe for millions of people.
We know ivermectin works, but how can we guarantee that the ivermectin you ordered is actually made right here in the United States – not in China? That’s where The Wellness Company comes in!
The Wellness Company and its freedom-fighting medical experts – like Dr. Peter McCullough and Dr. Kelly Victory – are the gold standard for providing safe, effective and affordable medical solutions. The Wellness Company’s doctors are the doctors who courageously told the truth during the pandemic and remain the nation’s leading voice for putting the health and well-being of the American people above the greed and profits of Big Pharma and the medical establishments.
Wellness company offering Ivermectin that is 100% made in America!
Not only made in America – but at a price you can’t beat
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(Note: The information provided is for generalized informational purposes only and should not be considered personal medical advice or used as a substitute for professional health care guidance. It is your responsibility to follow all applicable laws, regulations, and guidelines regarding the purchase, possession, and use of prescription medications. Thank you for supporting businesses such as featuring a sponsored message in this article and ordering through the links provided, thereby WLTReport benefits. We appreciate your support and the opportunity to keep you safe and healthy!)