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Christina Applegate says her ‘legs are sore’ in health update amid MS diagnosis

KANIKA SINGH RATHORE, 18/11/202518/11/2025

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christina applegate Years after revealing he was diagnosed with the disease, he has given his social media followers an update on his health multiple sclerosis In 2021.

He shared a video of himself on Instagram on Sunday dead to me actor explained that she can flare up sometimes Autoimmune conditions affecting the brain and spinal cord When she is stressed.

The clip shows her standing in front of a door while she looks off into the distance before making an inappropriate gesture with one of her hands.

“For those who don’t understand MS,” he captioned the post. “Our symptoms get worse when we are stressed or upset. I had something happen on Friday and have fallen 5 times. Legs are sore. So if you know someone with this kind of condition, maybe think…”

Commenters quickly responded to the post to wish Applegate well, whether through kind messages or heart emojis.

“Our symptoms get worse when we’re stressed or anxious,” Applegate explained in an Instagram post. ,Getty Images for Turner,

Fellow actor Jennifer Love Hewitt commented: “Sending you all my love,” while Heather Dubrow real housewives of orange county Wrote: “Love uuuuu.”

In August 2021, Applegate revealed that she was diagnosed with A few months ago M.S.And production on netflix dead to me He had to stay put for five months until treatment started.

She later revealed in December 2024 that she She inadvertently experienced one of her first symptoms of MS while filming the pilot. for her Netflix comedy, recalling a sequence in which her character Jane was running across a field.

“I remember falling that day. Hello, first sign of MS!” Applegate said in one of his episodes messy Podcast with Jamie-Lynn Sigler, featuring dead to me Producer Liz Feldman.

Feldman then chimed in, “I remember you losing your balance a few times, but it was very hard to figure out. I remember one time it happened it was really late at night, we were shooting maybe 14 or 15 hours, it seemed totally reasonable that someone would fall.”

Speaking about gradually realizing Applegate’s condition, Feldman said: “There’s no handbook for it. I could just sense that A, she was scared and B, that something was wrong, something in her body wasn’t working the way she wanted it to. I told her several times it’s just a TV show; we’re making a TV show and it’s so silly, you know, at the end of the day!

“I knew Christina well and knew something big was going to happen because she is extremely professional.”

Applegate has also spoken openly about the challenges she faced, including a neurological disorder feeling severely depressed due to debilitating pain,

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