The Blackwall tunnel at A102 has been closed for more than five hours crash,
The road is closed northward and only one lane is open to south due to the collision at 1.30 am on Wednesday, however, no further information about the incident has been confirmed.
Drivers have been warned of long delays and asked to use an alternative passage.
Transport to London (TFL) said: “North side traffic Falconwood and Southbound are back tailing Woolwich Flyover. ,
The tunnel has been discontinued from A2, Sand Sands Roundabout, Blackheath, A206, Woolvich Road flyover, Greenwich,
The London bus route 132 and SL4 are being diverted, the route SL4 with TFL is on diversion in both directions, while 132 is being diverted north.
Passengers are being urged to give extra time for their journey.