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Just 10 minutes exercise Can stop defecation every day cancer One study found that growth and accelerated DNA damage repair.
Researchers from Newcastle University found that brief periods of exercise can trigger rapid molecular changes in the blood.
The study said physical activity could protect against bowel cancer progression, but “the underlying biological mechanisms remain unclear”.
They collected blood samples from 30 overweight or obese but otherwise healthy men before and immediately after 10-12 minutes of exercise, in this case a cycling test.
They then exposed the intestinal cancer cells to pre- or post-exercise serum.
They found that strenuous exercise increased the concentration of 13 proteins in serum.
Many of these are associated with reducing inflammation and improving blood vessel function and metabolism.
When these exercise-induced molecules were applied to intestinal cancer cells in the laboratory, the researchers found changes in the activity of 1,364 genes, including those involved in DNA repair, energy production and cancer cell growth.
Writing in the International Journal of Cancer, the team said their findings provided a “potential mechanistic explanation” for the protective effect of exercise on bowel cancer.
Dr Sam Orange, senior lecturer in clinical exercise physiology at Newcastle University, who led the study, said: “Remarkably, exercise not only benefits healthy tissue, it also sends powerful signals through the blood that can directly influence thousands of genes in cancer cells.
“This is an exciting insight because it opens the door to finding ways to mimic or enhance the biological effects of exercise, potentially improving cancer treatment and, most importantly, patient outcomes.
“In the future, these insights may lead to new treatments that mimic the beneficial effects of exercise on cells repairing damaged DNA and using fuel to produce energy.
“These results suggest that exercise not only benefits healthy tissue but may also create a more hostile environment for cancer cells to grow.
“Even one workout can make a difference. A round of exercise that only lasts 10 minutes sends a powerful signal to the body.
“This is a reminder that every step, every workout counts when doing your best to protect your health.”
Genevieve Edwards, chief executive of Bowel Cancer UK, said: “Extensive research shows that people who are more physically active have a lower risk of bowel cancer, as well as many other cancers.
“We should aim for at least 150 minutes of activity a week, such as brisk walking, cycling or swimming.
“Other changes you can make to help reduce your risk of bowel cancer include eating more fiber from whole grains, legumes, fruit and vegetables, avoiding processed meat and limiting red meat, maintaining a healthy weight, quitting smoking and cutting back on alcohol.
“Changing your lifestyle can be a challenge, but we believe it’s worth it.”